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禽霍乱组织灭活油佐剂苗的研制

Studies on Inactivated Fowl Cholera Oil adjuvant vaccine

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【作者】 何顺华付锦楠龚小华刘尧服

【Author】 He Shunhua Fu Jinnan Gong Xiaohua Liu Yaofu(Institute of Microbiology.Jiangxi Academy of Sciences)

【机构】 江西省科学院微生物研究所江西省科学院微生物研究所

【摘要】 选用分离自急性禽霍乱病鸭的多杀巴氏杆菌,通过鸡(鸭)胚培养,制备组织灭活油佐剂苗。免疫接种后7~9天可产生免疫力,用同型或异型强毒禽多杀巴氏杆菌攻击,其保护率均在80%以上,保护期不少于4个月,疫苗保存期为半年。

【Abstract】 In order to prevent and control fowl cholera effectively caused by various serotypes Pas-teurella multocida ,a virulent Pasteurella multocida strain of poultry origin was selected to prepare inactivated oil adjuvant vaccine throrgh avian embryo propagation. The field tests showed that poultry got immunity 7-9days after inoculation,and the protective rate was above 80%,as challenged by homologous or heterollogous virulent Pasteurella multocida of poultry origin. Duration of immunity showed to be not less than 4 months and the expiry date of the prepared bacterin preserved at room temperature was more than half a year.

  • 【分类号】S859.79
  • 【被引频次】1
  • 【下载频次】39
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