【摘要】 本文报道８例急心肌梗塞患者的床旁冠状动脉（冠脉）内尿激酶（ＵＫ）溶栓治疗（ＰＴＣＲ）。８例患者ＰＴＣＲ顺利，其间病情稳定。冠脉造影时间为２５±４．４ｍｉｎ。５例患者ＰＴＣＲ后２１．７±９．２ｍｉｎ梗塞冠脉再通，再通时ＵＫ量１９．１±１１．３万Ｕ。３例患者持续ＰＴＣＲ达２ｈ，梗塞冠脉未能再通。结果表明，ＰＴＣＲ直接应用于床旁避免了传统ＰＴＣＲ需专用导管室和多科人员参与而难以应用于急诊的不足；床旁ＰＴＣＲ的有效再通时间短于静脉溶栓，更能有效地恢复冠脉血流和缩小梗塞范围。作者认为床旁ＰＴＣＲ是一种适合急诊溶栓的可行方法。更多还原

【Abstract】 Eight patients with AMI were treated by thrombolysis with bedside intracoronary urokinase. All patients were stable during thrombolytic therapy. The time of bedside coronary angiography was 25 ± 4. 4 minutes. Reperfusion was achieved in 5 patients after intracoronary urokinase and the time of reperfusion was 21. 7±9. 2 minutes, and the amount of urokinase used was 191 ± 113 thousand units. No reperfusion was observed in 3 patients after 2-hr thrombolytic therapy.It is concluded that (1) bedside intracoronary thrombolysis is time-saving as comparing with thrombolytic therapy in the catheterization room; (2) the effective reperfusion time of bedside intracoronary thrombolysis is much shorter than that of intravenous thrombolysis,and the former is more effective in recanalization of theinfarctrelated coronary artery. So it is a useful method for patients with AMI.更多还原