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有高血压家族史的正常血压者运动高血压及生化体液因子的变化
Exercise Hypertension and Hormonal Factors in Normotensives with Family History of Hypertension
【摘要】 对40例22~35岁正常血压但有高血压家族史者及20例无高血压病家族史者(对照组)进行运动负荷试验,前者14例出现运动触发性高血压(≥225/95mmHg),而静息血压和其他因素不能区分出这部分人。这部分人运动后肾素活性(PRA)、血管紧张素Ⅱ(AⅡ)、血浆5-羟吲哚物质(5-HIS)浓度均较正常血压者升高(P<0.05);静息状态内源性洋地黄因子(EDL)显著升高(P<0.001),运动后降低;血小板5-羟色胺运动后降低。有高血压病家族史者运动后心钠素(ANP)水平较对照组升高(P<0.05),其中运动触发高血压者升高程度显著,前列环素(PGI2)、血检索A2(TXA2)运动后效运动前升高,但差异无显著意义。
【Abstract】 This study compered cardiovaseular responses to exer-cise in normotensive subjects (aged 27. 00 3.11) at high risk (apeitive family history with hypertension in either or both parents,(n=40) with there at low risk (a negntive famial history of hyper-tension, n= 20) . During grnded bicycle exercie, 3516 (14/40) ofhigh risk subjects had exaggerated BP response (>225/95 nunHg) PRA, A2, 5-HT and ANP were incred significantly after exer-cise, compeed with thase in normotensives (P< 0. 05) . After exer-cise EDLS and platelet 5-HT decred, with no changes in PGI2 andTXA2.
- 【文献出处】 中国高血压杂志 ,Chinese Journal of Hypertension , 编辑部邮箱 ,1994年03期
- 【分类号】R544.1
- 【下载频次】71