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枳实有效成分的药理活性比较

A Comparison of Pharmacological Activities of Effective Constituents in Zhishi (Citrus aurantium )

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【作者】 胡盛珊王大元邱萍俞红

【Author】 Hu Shengshan; Wang Dayuan; Qiu Pin, et al(Jiangxi Provincial Institute of Medical Sciences,)

【机构】 江西省医学科学研究所!南昌330029

【摘要】 研究了枳实的有效成分,生物碱,黄酮甙,挥发油的药理活性,并进行比较。其中生物碱具有明显的升压作用;黄酮甙对大鼠离体肠平滑肌的收缩呈抑制作用;挥发油除对大鼠离体肠平滑肌的收缩呈先兴奋后抑制作用外,还能显著减少醋酸引起的小鼠扭体反应次数及小鼠自发活动次数,表现了一定程度的镇痛作用和中枢抑制作用。

【Abstract】 Pharmacological activities of the effective constituents: essential oils, flavonoids andalkaloids, in fruit of Citrus aurantium L. were compared. Blood pressure was increased markedly by transfusion of the alkaloids. Contractions of isolated intestines were iuhibited byflavonoids. Essential oils significantly decreased the rate and frequency of writhing syndromeinduced by ip acetie acid and spontaneous locomotor activities in the mice with the exceptionfexciting at first followed by inhibiting the isolated intestines,which displayed analgesia andoceutral inhibition to a certain extent.

【关键词】 枳实挥发油黄酮甙生物碱药理活性
  • 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,1994年08期
  • 【分类号】R285
  • 【被引频次】168
  • 【下载频次】1086
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