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“抗氧化复方”对大鼠应激性胃损伤的保护作用
Protective Effect of"Compound Antioxidant Herb"on Rat Gastric Injury Caused by Stress
【摘要】 选取丹参、丹皮等11味具有抗氧化作用的中药组成“抗氧化复方”,以大鼠束缚水浸应激性胃粘膜损伤为实验病理模型,观察抗氧化中药对应激性损伤的保护作用。结果:中药复方组和丹参注射组的胃粘膜损伤计数分别为8.5±2.31和19±4.24;血清脂质过氧化物(LPO)分别为10.74±0.94和11.80±1.06(nmol/ml),均较对照组(损伤计数39±6.50,LPO19.06±1.10nmol/ml)显著减轻(P<0.05)。初步证明抗氧化中药对应激性损伤有保护作用,复方效果可能优于单味药。
【Abstract】 Protective effect of Chinese medicinal Lerbs against gastric stress injury was studied.The compound antioxidant prescription used was composed of ten herbs, each of which had proven antiperoxidation action. Bound-soaked rats were used as victims of stress injury. In the two groups of rats under protection of the "prescription and injection of salvia" the indexes of gastric mucosa injury were 8.50±2.31 and 19.00±4.25, LPO in serum were 10.74± 0.94 and 11.80± 1. 06nmol/ml respectively. Both were significantly decreased as compared with the control group (39.00± 6.50, LPO 19.06± 1. 10nmol/ml ). These results signified that the antioxidant medicinal herbs, especially in compounded form, may prevent gastric stress injury
- 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,1994年01期
- 【分类号】R285
- 【被引频次】21
- 【下载频次】82