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金银花中绿原酸提取工艺探讨

Study on Extraction Methods of Chlorogenic Acid of Flos Lonicerae

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【作者】 林缎嫦宋劲诗吴应

【Author】 Lin Duanchang; Song Jinshi;et al.(Guangzhou Xingqun Pharmacentical Co.Ltd.Guangzhou,510120)

【机构】 广州星群(药业)股份有限公司

【摘要】 通过对水提,水提醇沉、稀醇提取和水提石灰乳沉淀的方法制备金银花提取物的比较研究,结果表明,水提石灰乳沉淀法,提取物和绿原酸得率均较低。经分析其原因,是绿原酸被碱性水解。因此,在中药制剂中,用此法制备金银花提取物是不合理的。制备金银花提取物仍以水提醇沉法较好。

【Abstract】 A comparative study on three extraction methods for extract of Flos Lonicerae,waterextraction,water-extraction and alcohol-precipitation and water-extraction and lime creamprecipitation has been carried out.The experimental results indicated that yields of both extract and chlorogenic acid were the least in the method of water-extraction and lime creamprecipitation as a result of that chorgenic acid is easily hydrolyzed in alkaline aqueous solution. So it is unreasonable to prepare the extract of Flos Lonicerae used in Chinese preparation by the water-extraction and lime cream-precipitation.It is suggested that it would be better to perpare the extract by the method of water-extraction and alcohol-precipitation.

【关键词】 金银花提取绿原酸
【Key words】 Flos Loniceraeextractionchlorogenic acid
  • 【文献出处】 中成药 ,CHINESE TRADITIONAL PATENT MEDICINE , 编辑部邮箱 ,1994年07期
  • 【分类号】TQ461
  • 【被引频次】143
  • 【下载频次】1263
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