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变应性皮肤病人血过氧化脂质与IgE水平变化

Level of Plasma LPO and Serum IgE in Patients with Allergodermia.

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【作者】 邓建红祝其锋陈秋霞吴志华刘慧明

【Author】 Deng Jianhong; Zhu Qifeng; Chen Qiuxia et al. Guangdong Medical College.

【机构】 广东医学院

【摘要】 测定了45例变应性皮肤病人的血浆过氧化脂质(LPO)以及血IgE含量。结果显示,患者血LPO和IgE含量均显著高于正常对照组(P<0.01及P<0.05)。患者血IgE水平升高与LPO变化是正相关关系(r=0.71,P<0.005)。提示在变应性皮肤病的病理过程中,IgE所介导的过敏反应可能与自由基脂质过氧化损伤有关。

【Abstract】 Level of plasma lipsma lipid peroxide (LPO) andserum IgE in 45 patients with allergodermia and 96 nor mal controls were measured, It was shown that thesefigures in the patients were significantly higher thanthat in the normal controls(P <0. 01, P<0. 05).Andthe elevation of the serum IgE level and the change ofLPO in the patients’ blood were in positive correlation(r=0. 71,P<0. 005 ).It is suggested that in the pathological process of allergodermia,allergic reaction mediated by IgE has relationship with the free radical lipidperoxidatic damage.

  • 【文献出处】 中国皮肤性病学杂志 ,THE CHINESE JOURNAL OF DERMATOVENEREOLOGY , 编辑部邮箱 ,1994年01期
  • 【分类号】R758.2
  • 【被引频次】4
  • 【下载频次】29
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