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下肢淋巴水肿患者的 99m锝—油酸多相脂质体动态淋巴显象

Dynamic lymph flow imaging in lymphede-ma of the lower extremities using tech-neium-labbelled polyphase liposome.

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【作者】 俞志昌马寄晓于建芳刘伟

【Author】 Yu Zei-cang, et al. Deparment of nuclear medicine, chest Hospital, Shanghai 200030

【机构】 上海胸科医院核医学科上海第六人民医院核医学科上海第九人民医院整形外科 200030

【摘要】 本文报道了用氯化恶锡还原99m锝标记油酸多相脂质体作为淋巴显象剂,对40例单侧下肢淋巴水肿患者进行淋巴引流动、静态观察,并作淋巴回流定量分析。结果表明:双足拇趾趾蹼间皮下注射显象剂15分钟后,健侧腹股沟淋巴结显影,以2小时后最清晰。腹股沟淋巴结时间——放射性曲线,观察到正常淋巴回流,增高淋巴回流和阻塞淋巴回流三种,放射性比值0.09~0.75。

【Abstract】 Dynamic imaging of lymphatic flow were performed in 40 patients complaining of ly-mphedema in unilalteral lower extramity. AH were injected intradermally with 8 mic (296 MBq) of 99mTc-polyphase liposome(99mTc-PL) in the medial web on the dorsum of both feet. 99mTc-Pl was labelled with 99mTC using the stannous chloride melhod, the labelling rate was over 90% (n = 10). Image acquisition for the lower pelvis and both thighs was started at 5 min after injection, the inguinal lymph node was visualized at normal side and more clear at 2 hours, the time-activity curver of both regions were also recorded. Following three patterns were recognized: Normal, Enhanced and Obstracted pattern. The counting ratio were from 0.06 to 0.75.

  • 【文献出处】 上海医学影像 ,Shanghai Medical Imaging , 编辑部邮箱 ,1994年02期
  • 【分类号】R817.4
  • 【下载频次】46
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