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氯已啶控释系统根管消毒作用的实验动物研究

Experimental research on chlorhexidine controlled release delivery system for root canal disinfection

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【作者】 凌均启樊明文罗雯魏国贤罗玲莉刘宁慧熊卫星陈智

【Author】 .Ling Jun-qi;Fan Ming-wen; Luo Wen et al.(School of Stomatology, Hubei Medical University, Wuhan,430070)

【机构】 湖北医科大学口腔医学院

【摘要】 对氯已啶控释系统的根管消毒作用进行了实验动物研究,发现将该药物封入髓腔7d后,细菌学培养均为阴性,并能稳定地保持抑菌状态;统计学分析,其效果明显优于对照组。提示氯已啶控释系统是一种有效的根管消毒剂。

【Abstract】 The purpose of the present study was to assess the root canal disinfection with a chlorhexidine controlled release delivery system by animal experiment.Root canal infection was induced in 120 teeth in dogs. After the instrumentation,canals were treated with the chlorhexidine collon pillet and formocresol 7 days using an anaerobic technique.The results indicated that the chlorhexidine controlled release system was more effective than others in rendering the root canal free of bacteria(P<0.05). The advantages of this antiseptic with a long lasting effect for the elimination of bacteria from the root canal and for prevention of reinfecton were emphasized.

【基金】 卫生部医学重点科研项目
  • 【文献出处】 牙体牙髓牙周病学杂志 ,CHINESE JOURNAL OF CONSERVATIVE DENTISTRY , 编辑部邮箱 ,1994年02期
  • 【分类号】R988.2
  • 【被引频次】1
  • 【下载频次】45
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