【摘要】 采用放免法检测61例甲亢和42例甲减患者血浆心钠索（ANH）水平。结果表明：甲亢未治组ANH显著高于甲亢缓解组、甲减未治组、治疗组及正常对照组，ANH水平与血清T3、T4、FT3和FT4存在正相关关系；甲亢缓解组、甲减未治组和治疗组ANH浓度与正常对照组比较无显著性差异，但甲减未治组ANH较甲减治疗组明显降低，提示甲状腺激素可调节ANH的合成和／或分泌，检测ANH对甲状腺功能异常的诊断和治疗效果观察具有一定的参考价值。更多还原

【Abstract】 Plasma atrial natriuretic hormone(ANH)values were evaluated in 61 hyperthyroidic patients and 42 hypothyroidic patients and 28 healthy subjects for comparison. In untreated patients with hyperthyroidism their ANH levels were markedly higher than that in patients with remitted hyperthyroidism,hypothyroidism and in controls. ANH values were positively correlated to serum T3 .T4. free T3 and free T4 concentrations. After administra tion of antithyroid drugs(ATD)-induced euthyroidism a normal range of ANH values was observed. No significant differences were found between hypothyroidic patients and controls,but ANH levels were much lower in patients who were euthyroid after replacement treatment. Observed data suggest that thyroid hormones may influence plas ma ANH concentrations and the detection of ANH is helpful for the diagnosis and treatment of hyper-and hypothy roidism.更多还原