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肾素系统对急性高原病的影响
The effect of Renin-Angiotensin system on the acute mountain sickness
【摘要】 对16例高原肺水肿(HAPE)、9例急性高原反应(HAAR)患者治疗前、后及14例刚入高原健康人用放射免疫分析法测定了血浆肾素活性(PRA)和血管紧张素Ⅱ(AⅡ)浓度,发现二者在HAPE和HAAR时均有不同程度增高,而PaO2低于6.665kPa(50mmHg)以下,碱中毒及心力衰竭时可使其明显增高,认为肾素系统在HAAR、HAPE的发生发展中可能起重要作用。
【Abstract】 Plasma renin activity (PRA) and angiotensin Ⅱconcentration in 16 cases with high altitude acute response(HAAR) and 14 healthy subjects were determined by radio-immunoassays, it was found that both the PRA and A Ⅱ concentration of HAPE and HAAR subjects were elevated in various degrees, especially when PaO2 is below 50 mm Hg and alkaosis as well as cardic failure were associated with. Thus we consider that the reninangiotensin system may play a remarkable role in the occurrence and development of HAPE and HAAR
【关键词】 高原肺水肿;
急性高原反应;
肾素-血管紧张素系统;
【Key words】 High altitude response; high altitude pulmonary edema; renin-angiotensin system;
【Key words】 High altitude response; high altitude pulmonary edema; renin-angiotensin system;
- 【文献出处】 西藏医药杂志 ,Tibetan Journal of Medicine , 编辑部邮箱 ,1994年02期
- 【分类号】R594.3
- 【被引频次】5
- 【下载频次】28