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脐血精氨酸加压素测定的临床意义
CLINICAL SIGNIFICANCE OF THE MEASUREMENT OF ARGININE VASOPRESSIN IN THE CORD BLOOD
【摘要】 本研究应用放射免疫法测定63例新生儿脐血和血清中精氨酸加压素(AVP)的含量变化,发现窒息儿脐血和静脉血AVP含量明显高于健康儿,提示新生儿窒息对在刺激新生儿体内释放AVP的机制中起重要作用,并发现胎儿宫内缺氧是一个潜在刺激AVP释放的因素。脐血AVP的含量可早期反映新生儿体内AVP的含量,因此,脐血AVP的测定,对于患儿高危状态的估计,指导早期治疗具有重要的参考价值。
【Abstract】 The concentrations of arginine vasopressin (AVP) in cord arterial blood and plasma in 63 newborns were rneasured with RIA. The cord and the plasma AVP concentrations were higher in asphysiated neonates than those in healthy neonates. We conclude that the massive release of AVP is associated with neonatal asphyxia and that fetal distress is a potnt stimulus to the release of AVP in the foetus. The concentration of cord AVP can early forecast the level of plasma AVP in newborn, The measurement of cord AVP is of great value to estimate dangerous condition of newborns and decide on therapeutic plan.
- 【文献出处】 新生儿科杂志 ,The Journal of Neonatology , 编辑部邮箱 ,1994年04期
- 【分类号】R722.12
- 【下载频次】18