节点文献
电针对沙鼠脑缺血及再灌注时脑电活动的影响
Effects of Electro-acupuncture on EEG During Transient Global Ischemia and Reperfusion in Gerbils
【摘要】 在急性沙鼠全脑缺血和再灌注模型上,应用计算机统计脑电总功率的方法,研究了针刺对脑缺血及再灌注各期脑电总功率的影响。发现缺血10min,脑电幅度受到严重抑制,总功率大大下降,再灌注后总功率难以恢复,对照组在120min恢复达最高水平时仅为缺血前的27.39±11.31%。电针组动物缺血10min再灌注后,脑电的恢复明显比对照组快,120min时恢复至缺血前的71.45±16.46%(P<0.01),240min时继续恢复至缺血前的75.27±18.43%。实验结果表明,电针能减轻脑缺血时脑电活动的抑制和促进再灌注后脑电活动的恢复。
【Abstract】 In the model of gerbil of acute global ischemia and reperfusion, we studied the effects of electroacupuncture (EA) on total power of EEG at different periods of global ischemia and reperfusion. The "Fengfu" (GV 16) and "Jinsuo" (GV 8) points were stimulated by electrical pulse with frequency 7 Hz and intensity of 5-6 mA for 30 min. Recording was made before ischemia and 0 min, 15min,30min, 60min, 120 min and 240 min after reperfusion respetively. The results were as follows:1. In hte control group, after 10 min of ischemia, the amplitude of EEG was severely inhibited,even became flatten, and the total power of EEG was significantly decreased to 1. 41 + 1. 29% .After reperfusion, the recovery of total power was very slow. The peak level of recovery occured at 120 min following reperfusion was 27. 39+ 11. 31%.2. In comparison with the control group, the EA remarkably improved the recovery of EEG after ischemia and reperfusion. The recovery of total power was 71. 45 + 16. 46% (P<0. 01), and 75. 27+ 18. 43 % (P<0. 01) at 120 min and 240 min after reperfusion respectively.These results strongly indicte that EA could reduce the EEG inhibition during global ischemia and improve the recovery after reperfusion
- 【文献出处】 针刺研究 ,Acupuncture Research , 编辑部邮箱 ,1994年01期
- 【分类号】R245.321
- 【被引频次】98
- 【下载频次】90