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山莨菪碱治疗前后糖尿病足坏疽病人的甲襞微循环变化

Changes of Mirocirculation in Diabetic Patients with Gangrenous Extremities Treated by Anisodamine

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【作者】 刘德辉朱西娥郑世荣李仕明

【Author】 Liu Dehui; Zhu Xi’e; Zheng Shirong; et al (General Hospital of Chinese PLA Air Force, Beijing 100036)

【机构】 中国人民解放军空军总医院

【摘要】 观察120例糖尿病足坏疽患者加用山莨菪碱治疗前后的甲襞微循环变化。结果表明:治疗前坏疽病人有不同程度的甲襞微循环障碍。山莨菪碱治疗后视野能见度有明显好转,清楚管袢、发夹形管袢、管袢数目增加,袢周和袢顶的出血、渗出减少或者消失;血液流态亦明显改善,团聚流减少(由85.7%降至24.3%)。管袢长度、宽度及输入、输出枝直径均有明显改善。甲襞微循环改善的同时,临床坏疽伤口也逐步好转、愈合,足坏疽的治愈率达83.3%。山莨菪碱能改善糖尿病肢端坏疽病人的甲襞微循环障碍,对坏疽伤口的愈合有益。

【Abstract】 Changes of microcirculation in 120 diabetic patients with gangrenous extremities are observed before and after treatment with anisodamine .There are marked microcirculatory disturbances in nailfold of diabeties. After treatment, microcirculation are improved greatly with: 1.the number and clearity of the capillary loops increased, 2. exudates and ecchymoses absorbed in most cases,3. blood cell aggregation lessened and blood velocity increased. 4. the diameters of capillary loops increased. At the same time, the gangrenous wounds healed gradually.It concluded that anisodamine which can improve the microcirculation in diabetics is benifit for the diabetic gangrene treatment.

  • 【文献出处】 微循环学杂志 ,CHINESE JOURNAL OF MICROCIRCULATION , 编辑部邮箱 ,1994年04期
  • 【分类号】R587.1
  • 【被引频次】5
  • 【下载频次】71
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