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甲状腺疾病血清rT3RIA及其临床价值

CLINICAL APPLICATION OF REVERSE T3 RADIOIMMUNOASSAY IN THYROIDAL DISEASES

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【作者】 吴应珍罗加吴国桢

【Author】 Wu Yingzhen;Luo Jia;Wu Guozhen(Chongqing University of Medical Sciences, Department of Nuclear Medicine, First Hospital, 630042)

【机构】 重庆医科大学附属一院核医学科

【摘要】 研究了182例甲状腺疾病患者治疗前后血清rT_3的变化,并与T_3、T_4等指标比较。结果表明、甲亢未治组和甲亢未控组rT_3均明显升高,甲亢已控组rT_3下降较慢较迟。甲低未治组rT_3明显下降,治疗后T_3、T_4恢复正常,rT_3仍未恢复正常水平。揭示血清rT_3的变化反映了机体在甲状腺功能改变时的一种代偿反应。开展rT_3检测对甲状腺疾病的诊断和疗效判断有实用价值。

【Abstract】 The change of rT3 in 182 patients with thyroidal diseases before , during and afteer treatment isstudied and compared with T3,T4. The results show that levels of rT3 in untreated and unrecovered hy-perthyroidism higher than control values. Serum rT3 slowly declines in patients with hyperthyredism re-covered after treatment with antithyroidal drugs.Serum rT3 concentrations fell significantly in patientswith hypothyroidism. However,there is significant difference between treated group with recoveryand normal controls.The mechanism and signi ficance of results are discussed in detail. It is pointedout that the measurement of serum rT3 may be considered as an effective method for evaluating the thy-roidal function and the effectiveness of medical treatment.

【关键词】 rT_3甲亢甲低
【Key words】 rT3 hyperthyroidism hypothyroidism
  • 【分类号】R581
  • 【下载频次】27
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