【摘要】 应用酶联免疫法检测天津地区90例慢性活动性乙型肝炎患者的抗丙型肝炎病毒(抗-HCV)抗体。对抗-HCV阳性患者的血清进行了Nested-PCR检测。90例患者有24例为抗-HCV阳性,阳性率为26.7％;24例抗-HCV阳性患者经PCR检测,8例为HCV RNA阳性。本组研究表明,天津地区慢性活动性肝炎患者血清中存在高水平的抗-HCV。在一定数量的患者中抗-HCV与HCV RNA并存,揭示确有HBV和HCV重叠感染,这种感染似以HBeAg阴性慢性活动性肝炎为常见,对重叠感染患者应分病室住院治疗。更多还原

【Abstract】 Anti-HCV antibody was determined in 90 patients with chronic active hepatitis B by an ELISA system. Anti-HCV positive sera were tested with Nested-PCR, Among the 90 patients, the sera from 24 patients were anti-HCV positive the positive rate was 26.7%. Of the 24 patients that were tested with PCR, 8 patients were HCV RNA positive. The results suggested that some patients with chronic active hepatitis suffered from superinfection of HBV and HCV in the Tianjin area, and these superinf ection patients should be separated during one’s hospitalization.更多还原