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地方性砷中毒地区人群血清酪氨酸水平变化的研究

Studies on the Change of Human Serum Tyrosin in Area Endemic for Arsenism

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【作者】 蒋玲鲁生业何敏段志凯牛培健

【Author】 Jiang Ling;Lu Shengye;He Min;et alInstitute of Environmental Medicine,Tongji Medical University,Wuhan 430030

【机构】 同济医科大学环境医学研究所!武汉430030内蒙古自治区临河市卫生防疫站!临河015000

【摘要】 对砷中毒地区及对照区的227人进行的研究发现,高砷饮水地区人群血清酪氨酸平均水平为14.20μg/L,与对照区12.20μg/L相比差异有极显著性意义(P<0.01)。还发现酪氨酸含量与砷中毒的一些症状如色素沉着、周围神经炎等有相关性。血清酪氨酸含量与发砷水平之间的等级相关系数为0.926。结果表明砷中毒可能导致血清酪氨酸含量升高并由此引起一些相应症状。

【Abstract】 227 persons from area endemic for arsenism and area taken as control were investigated and the average level of human serum tyrosin in people in area with high As drinking water was l4.20μg/L,significantly higher than that in control area(12.20μg/L).The relationships between the concentration of tyrosin and some of symptoms of arsenism,such as dyspigmentation,peripheral neuritis,were found.The rank corre1ation coefficinet between the concentration of tyrosin in serum and As content in hair was 0.926.The results showed that high As intaking might cause the rise of serum tyrosin and thus cause some symptoms of arsenism.

【基金】 卫生部科技基金
  • 【文献出处】 同济医科大学学报 ,Acta Universitatis Medictnae Tangji , 编辑部邮箱 ,1994年06期
  • 【分类号】R599
  • 【被引频次】2
  • 【下载频次】39
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