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清栓酶对过氧化脂质含量影响的研究
Rearch on Svate affecting the content of LPO in the serum
【摘要】 将54例冠心病、高血压病、糖尿病及脑梗塞病人,随机分为对照组与清栓酶组。对照组26例,常规药物治疗,清栓酶组28例,在常规药物治疗基础上加用蝮蛇清栓酶0.5u,稀释静脉点滴,一日一次,14天为一疗程。观察到蝮蛇清栓酶能明显升高超氧化物岐化酶活性(P<0.01),明显降低过氧化脂质的终末代谢产物丙二醛含量(P<0.01),说明蝮蛇清栓酶能有效减轻自由基损伤。
【Abstract】 The 54 cases patients with coronary heart disease,essential hypertension,diabetes mellitus and Cerebral infarct were divided into two groups at random:Comparativegroup (n= 26) were treated with normal drug, and Snak Venom antithrombotic Enzyme(Svate) group(n = 28)were applied not only normal drug,but also Svate, Which was diluted and intravenous droped.0. 5u/every time.once a day and the course of treatment is 14 days .After the research,We found that Svate can singnificantly arised activity of Superoxide dismutase(SOD) (p<0. 01) and reduced the leaval of ma1ondialdehyde (MDA)(P<0.01).It means that Svate can reduce the injury of Oxygen free radicals (OFR)effectively.
- 【文献出处】 蛇志 ,JOURNAL OF SNAKE , 编辑部邮箱 ,1994年02期
- 【分类号】R977.3
- 【被引频次】1
- 【下载频次】13