【摘要】 大鼠新生期腹腔注射谷氨酸单钠（ＭＳＧ），成年后，下丘脑弓状核（ＡＲＣ）的β一内啡肽（β一ＥＮＤ）免疫反应细胞减少６１．０％，血浆皮质酮基础值未受明显影响。在不可躲避的持续电刺激四肢足底３０ｍｉｎ后，ＭＳＧ组动物血浆皮质用水平显著升高（Ｐ＜０．０１）．这些结果与相应的对照组无明显差异，提示ＡＲＣ的β一ＦＮＤ能神经元在垂体一肾上腺皮质系统应激反应中不起重要的调节作用。更多还原

【Abstract】 n the experiment, the relationship of β--ettdorphin (P--END)neurous in hypothalamic axcuatenucleus (ARC) between plasma conicesterone (CS) reaction during sitess was investigated in maleadult rats treated neonatally with monosodium glututamate(MSG ). It was found that the number of β--END-- immunoreactive neurons of ARC in MSG--treated ratS decreased by 61. 0%. No significantdifference in the baseline CS level was observed between the MSG -- treated group and the controlgroup. After elcctrical footshock for "30 min, the CS level of both MSG--treated rats and control ratswere iucreased remarkably(P<O. ‘01 ). Tile results suggest that the β----END neurons in ARC do notplay an essential role in the regulation ’of Cs reaction of pituitary --- adrenocor tieal system during stress.更多还原