节点文献
不同温度保存的冻干卡介苗接种后的免疫效果
Immunologic Efficacy of Freeze-dried BCG Vaccine Stored at Different Temperatures
【摘要】 分别在-20℃、2~8℃和11~20℃,保存3个月的冻干皮内卡介苗活菌残存数分别为6.70×106/mg、1.26×107/mg、7.3×106/mg,接种492名新生儿,阳转率分别为83.56%、83.44%和82.46%,硬结平均直径分别为5.8、6.70和6.02mm,卡痕平均直径分别为4.68、4.11和4.27mm,表明冻干皮内卡介苗在-20℃冰柜中和11~20℃常温下保存3个月仍可使用。
【Abstract】 The residual viable counts of freeze-dried BCG vaccine stored at -2℃, 2~8℃ and 11~20℃ for 3 months were 6.70×106, 1. 26×107 and 7. 30×106/mg, respectively.192 infants were vaccinated with the vaccine stored at the 3 temperatures, and the result showed that the conversion rates were 83. 66%, 83. 44% and 82. 46%, respectively; and scleroma average diameters were 5. 8, 6. 07 and 6. 02mm, respectively; scar average diameters were 4. 68, 4. 11 and 4. 27mm, respectively. It proved that freeze-dried BCG vaccine still could be used after being stored at -20℃ or 11~20℃ for 3 months.
- 【文献出处】 中国生物制品学杂志 ,Chinese Journal of Biologicals , 编辑部邮箱 ,1994年04期
- 【分类号】R457.2
- 【被引频次】1
- 【下载频次】39