【摘要】 应用IHA法对1318名15～45岁育龄妇女进行了破伤风抗毒素水平测定，阳性率8.80％，保护率7.97％，GMT0．0026IU／ml。抗体阳性率随年龄增大呈下降趋势；城镇与农村育龄妇女的抗体阳性率和保护率均无明显差异。对其中379名18～35岁育龄妇女进行破类免疫，接种1，2，3针后的抗体阳性率，由免前的7.12％分别上升到88．34％、95．33％和100％，保护率由免前的6.33％分别上升到86．02％、93．93／和100％；GMT由免前的0.002IU／ml分别上升到0.26IU／ml、0．38U／ml和0．68IU／ml。各针次间的抗体阳性率、保护率和GMT均有显著差异。而各年龄组间的血清学效果则无明显差异。更多还原

【Abstract】 The tetanus anti-toxin (TAT) level of 1318 women aged 15~45 years were detected by IHA. The results showed that TAT positlve rate and protective rate were 8.80%and 7.97%, respectively, and GMT was 0.0026IU/mI. The antibody positive rates showed downward trends with increasing age. No significant difference was found between the TAT positive rates and protective rates of wornen resided in town and countryside. 379 of the women (18~37 years old ) were immunized wlth tetaflus toxoid (TT). After first, second and third dose were given, TAT postitve rates increased from 7.12% to 88. 34%, 95. 33%and 100%, respectively; protective rates increased from 6. 33% to 86.02%, 93.93% and 100%, respectively; and GMT increased from 0. 0021IU/ml to 0.26, 0.38 and 0.68IU/ml,respectively. There were slgniflcant difference among the TAT positlve rates, protective rates and GMT after administration of each dose. but no significant difference was found among the serological efficacy observed in various age groLlps.更多还原