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营养支持对纠正急性出血坏死性胰腺炎术后机体代谢改变的临床研讨
CLINICAL EVALUATION OF NUTRITIONAL SUPPORT IN CORRECTIONG POSTOPERATIVE METABOLIC CHANGES OF PATIENTS WITH ACUTE HEMORRHAGIC NECROTIC PANCREATITIS
【摘要】 1987年5月~1992年11月共收治急性出血坏死性胰腺炎患者28例,术后进行营养支持治疗,经过营养支持4周后(有4例未到营养支持4周即死亡),缩短了蛋白分解时间,纠正了低蛋白症和负氮平衡,同时也纠正了电解质紊乱和酸碱平衡失调。术后第7天血浆白蛋白值29.32±5.29g/L,经营养支持4周后明显上升达35.17±6.75g/L,血浆白蛋白值<35g/L的患者有24例,经营养支持4周后有17例纠正了低蛋白血症,20例纠正了负氮平衡。血浆白蛋白值≥35g/L的17例患者无1例死亡,死亡率为0,而血浆白蛋白<35g/L的7例患者有4例死亡,死亡率为57.1%。静脉营养和空肠造瘘灌注要素饮食,补充了足够的热量和蛋白质,是该病术后进行营养支持的可选方法。
【Abstract】 ltogether 28 cases of acute hemorrhagic necrotic pancreatitis in-patients were givennutritional support postoperatively from May,1987 to November,1992.The postopera-ative metabolic changes included disturbance of electrolyte,metabolic acidosis and alka-losis,hyperglycemia,and malnourished status such as hypoproteinemia and negativenitrogen balance. After four weeks’ nutritional support,except 4 cascs died within 4weeks,not OnIy electrolyte and acid-base imbalance were corrected, but also blood alb-umin was raised from 29.32 ±5.29g/L to 35.17 ± 6.75g/L,Of the 24 cases whose bloodalbumin was below 35g/L,20 had corrected negative nitrogen balance among which 17had corrected hypoproteinaemia with a mortality rate of zero. In the rest 7 cases the hy-poproteinemia was not corrected and 4 expired with a mortality of 57.1%.Parenteralnutrition and elemental diet through jejunal fistula are two feasible ways to give nutri-tional support to the patients of this disease.Clinical experience shows that patients’blood and urine amylase level keep normal during the period of nutritional support.Weconsider that nutritsonal support can correct postoperative metabolic changes and impro-ve tbe prognosis of the disease,and therefore is one of the important measares to cureacute hemorragic necrotic pancreatitis.
【Key words】 Acute hemorrhagic necrotic pancreatitis; Metabolic changes; Nutritional support;
- 【文献出处】 上海医学 ,SHANGHAI MEDICAL JOURNAL , 编辑部邮箱 ,1994年08期
- 【分类号】R576
- 【被引频次】3
- 【下载频次】30