【摘要】 细胞间粘附分子１（ＩＣＡＭ－１），又名ＣＤ５４，是一种重要的细胞表面粘附分子，属免疫球蛋白超家族．它可与鼻病毒以及整合素家族成员结合，参与炎症，普通感冒，变态反应及移植排斥反应．文章就其细胞分布、表达调节、结构功能、基因工程以及临床应用进行了综述．更多还原

【Abstract】 ntercellular adhesion molecule-1 (ICAM-1,CD54) . which belongs to the immunoglobulinsuperfamily. is one of the important adhesionmolecules on the cell surfaces. It can bind rhi-novirus and some of the members of the inte-grin family and involves the developments ofinflammation. commen cold. allergy and graftrejection etc. A brief review about the cell dis-tributions . expression regulation. structure ,fuctions and clinical applications of ICAM-1 isdescribed .更多还原