【摘要】 １９８８年１１月至１９９３年５月，我科的５７８例根治性切除的大肠癌病人中，２７例于术后１年内复发或转移。本文通过回顾性分析发现早期复发、转移与癌的部位、大小、形态、浸润深度及区域淋巴结转移、病理分化程度、生物学行为密切相关。并强调癌细胞的医源性种植和肿瘤切除范围不足是导致早期复发、转移的重要原因。早期复发、转移还可能与术中低血压、输血有关。进而提出了预防早期复发、转移的措施：①审慎地选择合适的术式；②强化术中无瘤操作观念；③术前、术后放疗预防局部复发；④提高外科技术；⑤ＣＥＡ水平的监测。更多还原

【Abstract】 Recurrence and metastasis of colorectal cancer within a year of resection indicates failure of surgicaltreatment.From November 1988 to May,1993,of 578 patients with colorectal cancer following radicalresection in our hospital,27 developed recurrencte or metastasis within a year.Through a retrospective analysis,we find that early recurrence and metastasis was correlated with the tumor site,size,appearance,invasive depth of tumor and regional metastasis of lymph nodes,histologic differentiation,blologic behavior ofcancer.It is emphasized that iatrogenic implantation of cancer cells and failure to excise the primary lesioncleanly with adequate margins were important factors causing early recurrence and metastasis. Early recurrence and metastasis were also related to hypotension,blood transfusion during the operation。Available methods for prevention of early recurrence and metastasis are suggested.They are:(a)choosing the proper operation carefully,(b)free tumor technique,during the operation;(c)pre or post operative radiotherapyfor prevention of local recurrence: (d)improving the technique of surgery;(e) monitoring CEA levels。更多还原