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4mmolK~+对利多卡因臂丛麻醉效果的影响

EFFECTS OF ADDITION OF 4mmol K~+ TO LIDOCAINE ON PLEXUS BRACHIALIS

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【作者】 安进莉张志琴潘玉贞张尚俭邓南桑田素明许航魏国华

【Author】 Anjinli Zhang ZhiQin Pan Yuzhen Zhang Shangjian Deng NanshangDepartment of Physiology ,Shihezi Medical CollegeXinjiang 832002Tian Shuming Xu Hang We GuohuaDepartment of Anaesthesea,No. 1 Affiliated HospitalShihezi Medical CollegeXinjiang 832008

【机构】 石河子医学院生理教研室石河子医学院一附院麻醉科

【摘要】 在58只家兔臂丛安放刺激电极,用JD—2型肌电图机记录桡侧腕伸肌的肌电图,分别观察0.5%利多卡因,0.5%利多卡因+4mmolKCL,0.7%利多卡因、0.7%利多卡因+4mmolKCL和1%利多卡因臂丛注射的麻醉效果,同时记录血压、心电图、呼吸和唇肌电并测定血钾浓度。结果表明:(1)利多卡因中加入4mmolK~+可以明显地缩短麻醉潜伏期和延长麻醉持续时间,即明显地提高麻醉效果;(2)4mmolK~+无增加利多卡因毒性反应的倾向。

【Abstract】 Anaesthesia Effects of 0. 5% lidocaine , 0. 5%lidocaine plus 4mmol KCL ,0. 7 % lidocaine , 0. 7%lidocaine plus 4mmol KCL and I% lidocaine on plexus brachialis were studies , and the pressure electrocardiogram , respiration , electromyograph of the upper lip and K+ density in the blood were recorded. The results indicate: 1. Lidocaine containing 4mmol KCL shortened the latent phase of anaesthetics and prolonged the duration or enhanced the effect of anaesthetics;2. Addition of 4mmol KCL resulted in no toxic reaction of lidocaine;3. The effect of 0. 5%lidocaine with an addition of 4mmol K+ was equal to that of I% lidocaine; 4. The duration of blockage of 0. 7% lidocaine with 4mmol K+ addition was longer than that of l% lidocaine.

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