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静脉注射三磷酸腺苷的瞬间致心律失常作用和安全性

Safety and proarrhythmia of intravenous adenosine triphosphate

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【作者】 何国平;

【Author】 HE Guo-Pin(Zhenjiang First People’s Hospital , Zhenjiang, 212002)

【机构】 江苏省镇江市第一人民医院;

【摘要】 给79例阵发性室上性心动过速患者分级递增快速静注三磷酸腺苷(ATP)332次,诱发缓慢心律失常(窦性心动过缓和1°~2°房室阻滞)135例次,占40.7%;快速心律失常(窦性心动过速、房性反复心搏、室上性心动过速、阵发性心房颤动、房性和室性早搏)254例次,占76.5%。除室上性心动过速外,均为一过性心律失常,皆无明显的血流动力学障碍。

【Abstract】 A total of 332 tests of intravenous bolus adenosine triphosphate(ATP) were performed during sinus rhythm or/and inducible supraventricular tachycar-dia (SVT) in 79 patients with paroxysmal supraventricular tachycardia. It was foundthat ATP induced 33 times (9. 9% ) of sinus bradycardia , 67 times (20. 2% ) of first-de-gree AV block (AVB), 20 times (6%) of second-degree type I AVB, 15 times(4. 5%) of second-degree type AVB, 194 times (58. 4%) of sinus tachycardia, 34times (10. 2%) of atrial reciprocal beats. 13 times (3. 9) of SVT, 8 times (2. 4%) ofoccasional atrial premature beats . 3 times(0. 9%) of paroxysmal atrial fibrillation and 2times (0. 6%) of occasional ventricular premature beats. All arrhythmias induced byATP were temporary except SVT and did not cause hemodynamic disturbance.

【关键词】 三磷酸腺苷; 心律失常;
【Key words】 Adenosine triphosphate; arrhythmia;
  • 【文献出处】 临床心电学杂志 ,JOURNAL OF CLINICAL ELECTROCARDIOLOGY , 编辑部邮箱 ,1994年04期
  • 【分类号】R969.3
  • 【被引频次】2
  • 【下载频次】36
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