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抗胸腺细胞球蛋白治疗再生障碍性贫血25例临床研究
Clinical Study on 25 Cares of Aplastic Anemia Patients Treated with Antithymocyte Globulin
【摘要】 本文报道抗胸腺细胞球蛋白(ATG)治疗25例再生障碍性贫血(再障AA)的疗效。总有效率72.0%,基本治愈+缓解44.0%,病死率16.0%。死亡的4例均为重型再障。80.0%AA病人治疗前T_4/T_8倒置,治疗后半数转为正常或好转。血清病反应轻者疗效明显优于反应重者(P<0.01)。
【Abstract】 Responsible effect of antithymoyte globulin (ATG) were evaluated in 25 cases with aplastic anemia.The total effective rate was 72.0%,cure and remmission rate were 44.0% and death rate was l6.0%.Four dead cases were all diagnosed as severe type(SAAⅠ 3,SAAⅡ1).The T4/T8 ratios were inverted in 80.0% before treatment and half of them were corrected and raised after ATG therapy.It was found that the responsible effect to ATG in group of mild serum sickness was apparently better than that of serere ones(P<0.01).
- 【文献出处】 临床血液学杂志 ,JOURNAL OF CLINICAL HEMOTOLOGY , 编辑部邮箱 ,1994年04期
- 【分类号】R556.505
- 【下载频次】51