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皮肌炎患者肌肉病变的观察与评价

Study on muscle changes in patients with dermatomyositis

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【作者】 罗燕

【Author】 Luo Yan (Institute of Dermatology, Shanghai Medical University)

【机构】 上海医科大学皮肤病学研究所

【摘要】 观察116例皮肌炎患者的肌肉病变,最常见的主诉是肌无力(81.03%)。68例患者有吞咽困难,常规胸片检查发现45例患者发生肺纹理增多,55例有EKG的异常。肌肉组织病理改变束周萎缩达30%有诊断意义。强调联合肌浆酶和24小时尿肌酸的测定,观察与评价内脏器官的累及对治疗和预后的重要性。

【Abstract】 The muscle changes were observed in 116 patients with dermatomyositis. Muscle weakness was the most common symptom(81.03%) . Dysphagia was found in 68 patients, increased pulmonary markings in 45 patients, and abnormal EKG in 55 patients. Histologically, perifascicular atrophy of muscle bundles was seen in 30% of patients. It is important to measure muscle enzymes and 24-hours urine creatine for the evaluation of internal organ involvement, treatment and prognosis in dermatomyositis.

【关键词】 皮肌炎肌肉病变
【Key words】 Dermatomyositis Muscle changes
  • 【文献出处】 临床皮肤科杂志 ,JOURNAL OF CLINICAL DERMATOLOGY , 编辑部邮箱 ,1994年06期
  • 【分类号】R593.26
  • 【被引频次】6
  • 【下载频次】48
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