【摘要】 本文对82例各种类型冠心病患者血浆5-羟色胺(5—HT)含量进行了测定。结果表明,各组冠心病患者血浆5—HT 含量均高于对照组,且急性心肌梗塞,心绞痛及心力衰竭组增高更为明显。其中心绞痛组以自发型心绞痛血浆5—HT 含量增加较为显著。结果提示,自发型心绞痛时病理生理改变更为严重.预后不良。本观察表明血浆5—HT 水平与疾病严重程度有关,并为寻找有效降低血浆5—HT 的药物治疗冠心病等提供理论依据。更多还原

【Abstract】 The levels of plasma 5—hydroxytryptamine(5—HT)were determined in 82 patients with different Coronary heart diseases (CHDs).The results showed that the 5—HT level was higher in each group with CHD than Contral group,much higher in the groups with acute myocardial infarction.Stenocardia and heart failure.The 5—HT level significantly increased in the patients with Spontanecus Stenodia.These findings Suggested that the changes in pathopthsiology in the Spontaneous Stenocardia was more serious and in prognosis and that the level of plasma 5—HTwas related to the seriouse degree of the diseases.Therefore,our study offers the theory basis for searching the drugs for effectively decrasing the pllasma 5— HT to treat CHD.更多还原