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固齿增骨散的研制和初步临床应用

A study of Zeng-Gu-San and observation of its primary clinical effects

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【作者】 樊明文凌均启程祥荣任铁冠王世平邓洪汛

【Author】 Fan Mingwen, Ling Junqi, Chen Xiangrong, et al.(Hospllal of Stomatology, Hulbei MedicalUniversity, Wuhan (430070 ))

【机构】 湖北医科大学口腔医学院

【摘要】 对传统处方修订后配制成固齿增骨散,经一系列实验室研究证实该制剂无毒副作用,具有促进成纤维细胞生长的作用,经临床初步应用对牙周炎及全口失牙患者具有防止牙槽骨进行性萎缩的效果。

【Abstract】 Abstract In this study, we have prepared a mixture of Chinese traditional medicinal herbs Zeng-Gu-San.On the basis of a series of laboratorial studies, we tried to use it for the patients with periodontitis and with complete demure.25 patients diagnosed as medium or serious adult periodontitis and other 14 edentulovs patients were selected in the test.The results of lab study showed the medicinal herbs had no acute and chronic toxicity, and had apparently effects on animal model.The clinical observation indicated that after taking the medicine. GI and the average PD of the patients in study group were clearly reduced than that before. TM had been continuously reduced through the whole observation period and it tended to be steady at the later period. X-ray photographic observation showed that after treatment of ZenGuSan. the density of alveolar bone in most cases had been increased. comparing with that before treatmemt.

  • 【文献出处】 口腔医学纵横 ,JOURNAL OF COMPREHENSIVE STOMATOLOGY , 编辑部邮箱 ,1994年04期
  • 【分类号】R988.2
  • 【被引频次】26
  • 【下载频次】170
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