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122例肝病患者肝内HDV,HBV感染的研究

Study of Hepatitis D,BVirus Infections in Liverof l22 Patients with Hepatopathy

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【作者】 唐宝璋刘宝源汤文辉冯毓正杨亚英张永生

【Author】 Tang Baozhang Liu Baoyuan Tang Wenhui Feng Yuzheng Yang Yaying Zhang Yongsheng(1)Department of Infections Diseases 2) Department of Pathology,The First Affili-ated Hospital,Kunming Medical Coltege,Kunming 650032)

【机构】 昆明医学院第一附属医院传染科

【摘要】 本文对122例各型肝病患者用ABC法同时检测肝内HDV及HBV抗原。结果显示,HBsAg和/或HBcAg检出率为27.87%(34例),其中HBcAg为13.22%(16例),HBsAg为18.18%(22例),两者无显著性差异(P>0.05).HDAg检出率为4.92%(6例),这6例丁型肝炎血中均检出HBsAg和抗一HBc,为慢性肝炎.在重肝、肝硬化和肝癌患者的肝内未检出HDAg.说明我国肝炎病毒感染仍以HBV为主,HDV感染率明显低于欧美,HDV感染与HBV感染关系密切,HBV感染合并HDV感染时易使病程慢性化。

【Abstract】 ntigens of HBV and HDV were determined by ABC method in liver tissues of l22 pa-hents with various types of hepatopath.34 out of the l2l cases were HBsAg and / orHBcAg positive( 27. 87 %).The positive rates of HBsAg and HBcAg were l3.33% (16/121) and l8.18%(22 / l2l)respectively.Their difference was not statistically signi一ficant(P>0.05).A positive rate of HDAg was 4.97%(6/ l22).Among the 6 cases of hepatitis D。HBsAg and anti一HBc were detected in blood.The 6 cases were chronic hepatitis。HDAg was not detected in liver specimens of patients with severe hepatitis,hepatocirrhosis and hepatocellular carcinoma。The results above showed the infection of hepatitis virus was still main HBV in chinese。The infection rate of HDV in china was obviously lower than that in the countries in Europeand America,The relationship between HBV and HDV is close。For mixture infection of HBV and HDV,it turns to be chronic disease easily。

【关键词】 HDAgHBsAgHBcAg
【Key words】 HBsAg BHcAg HDAg
  • 【文献出处】 昆明医学院学报 ,ACADEMIC JOURNAL OF KUNMING MEDICAL COLLEGE , 编辑部邮箱 ,1994年03期
  • 【分类号】R512.6
  • 【下载频次】13
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