【摘要】 用含５％葡萄糖的利多卡因局麻药液及含１：２０万肾上腺素的利多卡因局麻药液，择期在硬膜外麻醉下行下腹及下肢手术各２０例，两组病人麻醉诱导量（初量）均为１７ｍＬ．观察两组的诱导时间，初量维持时间及单位时间用药量．结果诱导时间两组间无显著性差异（Ｐ＞０．０５），初量维持时间及单位时间用药量则有显著性差异（Ｐ＜０．０１）．结果提示，硬膜外麻醉时，局麻药液中加入葡萄糖后麻醉维持时间较加入肾上腺素时长，毒性反应发生率亦降低．更多还原

【Abstract】 comparison between mixing with glucose and adrenaline in local epidural anesthesiawas made. Fortv cases were chosen randomly from the ASA Ⅰ or Ⅱ patients and divided in-to two groups: Group A, composed of 20 patients, were treated by 1.6% lidocaine mixedwith 5% glucose. Group B,also composed of 20 patients,by 1.6% lidocaine mixed with1/200000 adrenaline. Every patient received 17 mL as the first dose. The results suggest thatthe first dose in Group A lasted longer than Group B(P<0.01).Therefore,to extend theanesthesia effective time and to reduce the drug poisoning,it is better to mix lidocaine withglucose than with adrenaline in local epidural anesthesia.更多还原