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三种强心甙正性肌力作用效能比较研究
A COMPARATIVE STUDY OF THE EFFECT OF THREE GLYCOSIDS ON THEIR INOTROPIC ACTION
【摘要】 本实验采用离体兔心房标本测定了三种强心甙的正性肌力作用效能(即加强心肌收缩力的最大效应)。实验结果表明,毒毛旋花子甙K、西地兰和地高辛的效能是不同的,当达到最大效应时,可使兔心房标本的收缩振幅比给药前分别增加66.3、42.9和38.0%。这些差别有显著的统计学意义,其中毒毛旋花子甙K是最有效的正性肌力药物。
【Abstract】 In this tudy the effect of three glycosides on their inotropic action was tested with isolated rabbits’ atria.The results indicated that the effect of strophanthine K,lanatoside C and digoxin was different. When their maximal efficiercy was obtained, strophanthine K, lanatoside C and digoxin could increase the amplitude of contraction by 66.3,4.29 and 38.0% respectively in the isolated rabbits’ atria.The difference are statistically significant. Of these three glycosides strophanthine K is the most effective inotropic drug.
【关键词】 毒毛旋花子甙K;
西地兰;
地高辛,兔心房;
效能比较;
【Key words】 Strophanthine K; Lanatoside C; Digoxin; Rabbit atria; Efficieney comparison;
【Key words】 Strophanthine K; Lanatoside C; Digoxin; Rabbit atria; Efficieney comparison;
- 【文献出处】 锦州医学院学报 ,JOURNAL OF JINZHOU MEDICAL COLLEGE , 编辑部邮箱 ,1994年01期
- 【分类号】R972.1
- 【下载频次】64