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门脉高压性胃粘膜超微结构特征

ULTRASTRUCTURAL CHARACTERISTICS IN PORTAL HYPERTENSION GASTRICMUCOSA

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【作者】 陈佩兰陈乃玲刘超英彭晓君邓燕林贾克明

【Author】 Chen Peilan, Chen Nailing, Liu Chaoying, Peng Xiaojun , Deng Yanlin , Jia Keming.Institute of Liver Disease, General Hospital of Beijing Command, PLA. Beijing100700

【机构】 北京军区总医院

【摘要】 为进一步认识门脉高压性胃粘膜病变特点,利用透射电子显微镜对14例肝硬变食管静脉曲张病人及7名健康成人胃体上部胃粘膜进行了对比观察。发现门脉高压病人胃粘膜微静脉增多且管腔扩大;毛细血管内皮细胞肿胀导致管腔狭窄和基底膜增厚;粘膜下层动-静脉短路等特征。作者认为上述改变可能为肝硬变门静脉压力增高所致。

【Abstract】 The alterations in mucosa of upper gastric body in 14 cases of liver cirrhosis with portalhypertension and 7 endoscopically normal subjects without chronic liver diseases were observed by trans-mission electron microscope. In liver cirrhosis with portal hypertension cases,venules in gastric mucosawere remarkably increased and dilated. Marked hypertrophy of capillary endothelium resulted in the re-duction of lumens. Basement membrane was thickened. Submucosal arteriovenous communications in-creased in number. We believe that they are caused by the gradual increase of portal venous pressure incirrhotic patients.

【关键词】 肝硬变胃粘膜超微结构
【Key words】 Liver cirrhosisGastric mucosaUltrastructure
  • 【文献出处】 解放军医学杂志 ,MEDICAL JOURNAL OF CHINESE PEOPLE’S LIBERATION ARMY , 编辑部邮箱 ,1994年01期
  • 【分类号】R575.210.2
  • 【被引频次】6
  • 【下载频次】22
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