A New Genetically Engineered Vaccine for Animal Growth Promotion

【摘要】 <正> The chemically synthesized somatostatin (ss) gene was fused in phase with the 3′-end ofhepatitis B virus surface antigen (HBsAg) gene.The fusion gene HBs/ss was then recomhined into thegenome of vaccinia virus.This recombinant virus (w-HBs/ss) can express hybrid HBsAg/ss particles whichpresent ss determinants on their surfaces,thereby bearing a good immunogenicity.This new strategical vac-cine of ss can elicit the production of antibody capable of neutralizing ss in the plasma,and consequently en-hance the growth of animals.更多还原

【Abstract】 The chemically synthesized somatostatin (ss) gene was fused in phase with the 3′-end of hepatitis B virus surface antigen (HBsAg) gene.The fusion gene HBs/ss was then recomhined into the genome of vaccinia virus.This recombinant virus (w-HBs/ss) can express hybrid HBsAg/ss particles which present ss determinants on their surfaces,thereby bearing a good immunogenicity.This new strategical vac- cine of ss can elicit the production of antibody capable of neutralizing ss in the plasma,and consequently en- hance the growth of animals.更多还原