【摘要】 通过双亚氨酯盐酸盐与手性胺醇反应简便地合成了二取代双(口恶)唑啉衍生物,并将其与铜配位运用于重氮醋酸酯对烯烃的不对称环丙化反应,不对称诱导反应光学产物收率最高达95%d.e.更多还原

【Abstract】 Bis-oxazolines were easily prepared from diethyl propanediimidoate dihydrochloride and chiral amino alchols. These bis-oxazolines were successfully applied to the reaction of alkyl diazoacetate with olefin to give optically active alkyl cyclopropanecarboxylate. The highest enantioselectivity achieved 95% d. e. in the catalytic cyclopropanation of iso-butene.更多还原