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198例囊虫病的免疫学检测与分析

DETECTION OF ANTIBODY IN 198 CASES WITH CYSTICERCOSIS

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【作者】 武峰晋雪香毛福荣王中全崔晶

【Author】 Wu Feng et al(Department of Parasitology,Henan MedicaI University Zhengzhou 450052)

【机构】 河南医科大学寄生虫学教研室

【摘要】 本文收集了198例皮肌型及脑型囊虫病,分别经活检、计算机断层扫描(CT)或核磁共振成像(MRI)诊断为囊虫病,并具有相应临床症状。应用间接荧光抗体试验(IFAT)检测本组病人血清抗体,阳性率分别为皮肌型66.67%(54/81),脑型82.05%(96/117)。对脑型中20例患者的脑脊液和血清抗体进行检测对比,阳性率分别为55%和85%。实验表明,IFAT对于脑型囊虫病的抗体检出率高于皮肌型,在检测抗体诊断脑囊虫病时应首选血清标本。

【Abstract】 In the years 1992~1993,198 cases of cysticercosis who were refered to de-partment of parasitology Henan Medical University were collected.The subcutaneous andmuscular cysticercosis was confirmed by biopsy. The cerebral cysticercosis was proved bycranid computed tomographic(CT)scans or magnetic resonance imaging (MRI)and the ma-jority of patients had clinical manifestations such as headache,seizures and stroke. Indirectfluorescent antibdy test (IFAT)was used to detect the antibdy in serum of the patients.The positive rate of the subcutaneous and muscular cysticercosis was 66.67%(54/81),andthe cerebral cysticercosis was 82.05%(96/117).For antibody detection in cerebrospinal fluid(CSF)of 20 patients with cerebral cysticercosis,the positive rate was 55%(11/20 ),andmeanwhile,the serum antibody positive rate of the 20 patients was 85%(17/20).The resultsshow that the antibody detection rate on cerebral cysticercosis is higher than that in subcuta-neous and muscular cysticercosis. The serum samples are of choice for detecting antibody indiagnosis of cysticercosis.

【基金】 河南省卫生厅资助课题
  • 【文献出处】 河南医学研究 ,HENAN MEDICAL RESEARCH , 编辑部邮箱 ,1994年01期
  • 【分类号】R532.33
  • 【被引频次】1
  • 【下载频次】16
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