【摘要】 本文报告２１例基底动脉尖综合征（ＴＯＢ）的患者。ＴＯＢ是指基底动脉尖部２ｃｍ内所属７条动脉之一或一条动脉以上动脉闭塞所致的丘脑、中脑、枕叶或颞叶内侧面梗死所致的综合征。病因多为外来血栓栓塞，临床表现复杂多样。以眼球运动功能障碍和瞳孔异常及波动性意识障碍为特征性表现。ＣＴ有中脑、颞叶、丘脑枕叶等处合并或单独受损的征象，脑血管造影对确定某一支血管闭塞有重要意义。本文还对该病的发生机理和临床诊断进行了初探。更多还原

【Abstract】 The "Top of Basilar" Syndrome (TOB) is a occlusive vascular disease of the rostral basilar artery, in which one or more of seven arteries in the top regions of the basilar artery occlude and causr infarction. The syndrome is often due to thromboembolism. In the present article, we report 21 cases with TOB, Clinical signs were complicated and varied, but the most common signs are disorders of ocular movement, abormal pupils and disturbance of consciousness. The hyperglycemia, hyperlipemia, atrial fibrillation by rheumatic valvular heart disease, as well squamous cell carcinoma of uterus were found by physical and laboratory examination. The syndrome is diagnosed by embolus source, clinical manifestations in accordance with the circulatory disturbance in the top region of the basilar artery, and CT or cerebral angiography verification. The patients were treated by blood vessel dilation, blood volume supplement as well as light quantum blood therapy. The symptoms were improved remarkablely in 16 of 21 cases (76 percent).更多还原