【摘要】 研究了不同分子量的黑木耳酸性杂多糖６个分级和未分级试样的生物活性．小鼠腹腔注射试验结果表明该多糖具有促进白细胞增加、抗凝血和降低血小板的作用，其活性随着多糖分子量和糖醛酸含量降低而增大，即生物活性依赖于多糖在水中的溶解度．用酸碱返滴定法测定多糖中糖醛酸含量，实验结果与文献值一致．更多还原

【Abstract】 The bioactivities for six fractionated and unfractionated samples of acidic heteropolysaccharide of Auricularia auricula-judae having different molecular weights (Mw and Mn) were studied. The results obtained by i. P. injection in mice show that the polysaccharides have bioactivities in motivating the growth of leucocytes, anticoagulation and decreasing blood platelet count,and the effects increase with the decrease of molecular weight and glucuronic acid content in the range(200×10￣4>Mw>18×10￣4; 16%>CGA>9. 7%)studied.We conclude that the bioactivities depend seriously on the solubility of the polysacchride in water. In addtion,a method of acid-base back-titration used for determination of glucuronic acid content(CGA) of the polysaccharides was established,and its experimental results are in good agreement with data in literature.更多还原