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淋巴因子相应靶细胞的小剂量辐射效应
EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED
【摘要】 观察了单次小剂量X射线全身照射后C57BL/6小鼠胸腺细胞IL-1反应性和脾细胞IL-2反应性的变化。发现在100mGy以内的小剂量照射后,整个胸腺和脾脏的细胞数趋于增多,胸腺细胞对IL-1的反应性和牌细胞对IL-2的反应性趋于增强,体外照射IL-2依赖株CTLL-2细胞亦出现同样的反应趋势,但统计学处理与对照组比较均无明显差异。
【Abstract】 The changes of reactivities of thymocyte to IL-1 and splenocyte to IL-2 were studied in C 57 BL/6 mice after whole body X-irradiation with low doses. It was found that the number of thymocyte and splenocyte was increased,the reactivities of thymocyte to IL-1 and splenocyte to IL-2 also showed a tendency to increase after X-irradiation with low doses below 100 mGy, but the increase was statisticaly not significant. There was a same effect of low dese radiation on the CTLL-2, growing dependent on IL-2, irradiated in vitro.
【关键词】 小剂量辐射;
白介素1;
白介素2;
CTLL-2细胞;
【Key words】 Low dose radiation; Interleukin-1 (IL-1). Interleukin-2 (IL-2); CTLL-2 cell;
【Key words】 Low dose radiation; Interleukin-1 (IL-1). Interleukin-2 (IL-2); CTLL-2 cell;
【基金】 国家自然科学基金
- 【文献出处】 辐射研究与辐射工艺学报 ,Journal of Radiation Research and Radiation Processing , 编辑部邮箱 ,1994年02期
- 【分类号】Q691
- 【下载频次】29