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喉部分切除术的临床评价

An analysis of curative effect of partial laryngectomy in 135 patients of laryngeal carcinoma

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【作者】 许安廷王天铎栾信庸张大良姜玉芳

【Author】 Xu Anting ; Wang Tianduo ; Luan Xinyong ; Zhang Daliang ; Jiang Yufang[the Department of Otolaryngology,Affiliated Hospital of Shandong Medical University,Ji-nan 250012]

【机构】 山东医科大学附属医院耳鼻咽喉科

【摘要】 对资料完整的135例喉部分切除术的喉癌患者进行了疗效分析,3、5年生存率分别为86.7%和83.8%。Ⅰ和Ⅱ期的3、5年生存率为93.8%和90.6%,高于Ⅲ和Ⅳ期(76.4%,70.4%);声门区癌3、5年生存率(90.5%,87.7%)高于声门上区(73.3%,66.7%)。局部复发14例,颈部转移11例,远处转移2例,14例行再次手术治疗,术后2年生存率为64.3%。所有患者的发音功能均可保留,但受到不同程度的损害;62.9%的患者术后有不同程度的误吸,经训练后大多可正常进食,只有1例需二次手术关闭喉口。76.3%的患者可拔管,在已拔管的患者中有21.4%诉有轻度呼吸不畅,但不影响日常工作。提出喉癌患者行喉部分切除术后的疗效评价应包括两个方面:肿瘤切除的彻底性(生存率)和喉功能恢复的程度。

【Abstract】 Abstract The effectiveness of partial laryngectomy in 135 patients of laryngeal earcinoma were re-ported. Our patients population consisted of 120 males and 15 females ranging in age from 30 to 74 years. The survival rates of three and five years were 93.8% and 90.6%in stage T1-T2,76.4%and 70.4%in stage T3-T4 respectively. The three and five years survival rates were 90.5%and 87.7%in glottic earcinoma,73.3%and 66.7%in supraglottic carcinoma. There were local recurrence in 14,neck metastasis in 11,distant metastasis in 2. Salvage surgery were performed in 14 cases, with a two years survival rate of 64.3%. The phonate despite voice quali-ty were reserved in all cases. Only one case had closure laryngeal inlet for severe inspiration,and there were inspiration of various degree in 62.9%, but most of them can eating normally after training.The decannulation rate was 76.3%。 The problems of determine the curative effect in partial laryngectomy were discussed.

  • 【分类号】R739.65
  • 【被引频次】15
  • 【下载频次】44
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