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克山病患者红细胞膜磷脂组成及服用磷脂对其影响的研究

STUDY ON PHOSPHOLIPID COMPOSITIONS OF ERYTHROCYTE MEMBRANE IN KESHAN DISEASE PATIENTS

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【作者】 罗坤刘忠英安汝国姜熙罗李庆才荣慧

【Author】 Luo Kun, et alInstitute of Endemic Disease, Norman Bethune University of Medical Sciences

【机构】 白求恩医科大学地方病研究所吉林省进出口商品检验局吉林省进出口商品检验局

【摘要】 克山病患者红细胞膜中PC、PE和SM均低于病区对照,主要PL的百分组成PC低于对照,SM和老化指数SM/PC略高于对照。患者口服PL3个月后,PE和PL总量有所提高,SM的百分组成和SM/PC下降到对照以下。证明克山病患者红细胞膜中PL含量和百分组成都发生了变化,服用PL可取得改善。

【Abstract】 The results showed that the PE, PC and SM contents of erythrocyte membrane in KD patients were all slightly lower than those in the control group from endemic area. The PC percentage of erythrocyte membrane in KD patients were slightly lower than that in the control group from endemic area and the percentage of SM and the ageing index SM/PC was somewhat higher than that of control group. After three months of PL orally taking, the PE and the total PL amounts in KD patients increased. The SM percentage and SM/PC decreased. This experiment appeared that the principal PL contents and their percentage of erythrocyte membrane in KD patients changed in comparision with the control group, and this change can be improved by the orally taking of PL.

【关键词】 克山病红细胞膜磷脂
  • 【文献出处】 中国地方病防治杂志 ,Chinese Journal of Control of Endemic Disease , 编辑部邮箱 ,1994年05期
  • 【分类号】R542.3
  • 【下载频次】21
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