【摘要】 用单光子吸收法(SPA)测定30例6～32岁神经型地方性克汀病人的前臂骨矿物质含量(g/cm~2)。结果发现克汀病人骨矿含量普遍较低,克汀病组除25岁以上者外其骨矿含量均显著低于正常对照组;克汀组骨矿低下者的检出率男66.6％、女83.3％、儿童100％,同组相应x线骨片骨质疏松的检出率男72. 2％、女83.3％、儿童100％;克汀组平均身高与体重显著低于对照组,但甲状腺功能与正常对照无显著差异。以上结果提示,克汀病人多数有骨质疏松或骨矿低下,后者用SPA容易查出,与x片结果相似,有实用价值。本文讨论了神经型地方性克汀病人骨质疏松的有关因素。更多还原

【Abstract】 The bone mineral content (BMC) in forearm on 30 cases (18 males and 12 females aged from 6 to 32 years old) of neuro-endemic cretinism was measured by using single-photon absorptiometry (SPA). The results showed that BMC (area density g/cm2) in cretinism groups was lower than that in normal control groups. The difference between two groups was significant, except the subjects aged more than 25 years old. The detect rate of low BMC in cretinism group was 66. 6% in men, 83. 3% in women and 100% in children. The detect rate by bone radiograph in the same group showed that osteoporosis was 72. 2% in men, 83. 3% in women and 100% in children. The positive results by two methods were similar. The mean of body height and weight in cretinism group were significantly lower than that in control group, but thyroid functions of cretinism group were normal or almost normal. These recalls showed that osteoporosis generally existed in neuro-endemic cretinism , and that it could be easily found by using SPA. The paper discussed related factors to osteoporosis in neuro-endemic cretinism.更多还原