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蚕蛹虫草镇静及性激素样作用的研究

The calmative and sex hormone-like effect of Cordyceps militaris(L)Link(Cantherea pernyi)

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【作者】 刘洁杨旭陈正梁曼义李景洛

【Author】 Liu Jie, Yang Xu, Chen Zhcng, Liang Manyi, Li Jingluo(Dept,of Pharmacol,N. Bethune Univ.of Med.Sci;*Jilin Prouincial Institute of Silkworm Breeding)

【机构】 吉林省蚕业科学研究所

【摘要】 蚕蛹虫草水煎剂灌胃给药,对小鼠具有镇静作用,能减少小鼠自主活动次数,协同戊巴比妥钠催眠作用,抗惊厥,提高耐疲劳能力;明显升高正常大鼠血浆皮质醇及睾丸酮含量,增加大鼠体重及包皮腺、精囊、前列腺的重量,而且增加去势大鼠精囊一前列腺重量,具有雄激素样作用。其作用性质及强度与冬虫夏草相似。

【Abstract】 Cordyceps militaris(L)Link’s decoction possesses a calmative effect on mice;when used in combination with pentobarbital,it synergized the hypnotic action of the latter, ex-hibiting an anti-convulsive effect,increasing the anti-fatigue ability of the experimental animals,and the plasm content of cortisol and testesterone was elevated obviously. It increased not onlythe weight of the preputial glands, the seminal vesicle and prostate, but also the seminal vesicle-prostate of the castrated mice,exerting a male-hormone-like effect. The results showed that it’seffect is quite similar to that of cordyceps sinesis(Berk)Sacc.

  • 【文献出处】 白求恩医科大学学报 ,JOURNAL OF NORMAN BETHUNE UNIVERSITY OF MEDICAL SCIENCE , 编辑部邮箱 ,1994年01期
  • 【分类号】R282.740.5
  • 【被引频次】53
  • 【下载频次】284
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