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利用体表瞬变温度无损检测生物体温度依赖型热物性

Noninvasive Measurement of Organism Bady Temperature Dependant Thermal Properties by Using Transient Temperature of Bady Surface

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【作者】 刘静任泽霈王存诚

【Author】 Liu Jing; Ren Zepei; Wang Cuncheng(Tsinghua University, Beijing 100084)

【机构】 清华大学热能工程系

【摘要】 作者提出一套可用于同时确定生物传热方程─Pennes方程中随温度变化的导热系数K、导温系数a、血液灌注率Wb及代谢热产率Qm的新方法。文中主要讨论上述参数随温度呈一次方变化的情况,同时考虑空间和温度依赖问题等更复杂的情形亦可用此方法解决。在此基础上,作者发展了一种简单适用且完全无创的检测技术,采用Householder变换法求超定方程,获得导热率及灌注率关于温度变化的线性表式,结果与有关文献数据吻合。本方法可为研究生物传热学、热生理学以及实现肿瘤热疗中的实时监测打下一定的基础。

【Abstract】 A nwe method for identification of the temperature-dependant thermal conductivity coefficient K、thermal diffusion coefficient、blood perfusion rate Wb and metabolic rate Qm is presented. In this paper, the discussion is mainly about this condition: the above mentioned coefficients are linearly dependant with temperature change. For more complex case, such as simultaneous space and temperature-dependant problems can be solved by the same method.This method is not limited by the number of unknown parameters. As long as the number of internal measurement points and transients states is enough, and the measured temperatures are accurate, the unknown parameters can be obtained reasonably. Based on the above mentioned method, the authors developed a simple, practical and noninvasive measuring technique. The househdder transformation method was used to solve the over determined equations, and lineal expressions of the thermal conductivity and prefusion rate dependant on temperature were obtained. These results coincide with those in literatures. This method also could be the basis for further research of bioheat transfer, thermophysiology and real-time monitoring of the cancer thermal therapy.

【基金】 国家自然科学基金
  • 【文献出处】 北京生物医学工程 ,BEIJING BIOMEDICAL ENGINEERING , 编辑部邮箱 ,1994年04期
  • 【分类号】R318.03
  • 【被引频次】3
  • 【下载频次】59
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