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放射与放射结合瘤内药物注射治疗原发性大肝癌的疗效观察

Observation of Irridiation versus Irradiation Combined with Intrahepatic Injection of Drugs in Treating Large Primary Liver Cancer

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【作者】 刘鲁明于尔辛

【Author】 Liu Luming, Yu Erxin, Department of Liver Cancer Research, Cancer Hospital, Shanghai Medical University, Shanghai

【机构】 上海医科大学附属肿瘤医院上海医科大学附属肿瘤医院 浙江中医学院附院肿瘤科

【摘要】 本文报告62例大肝癌(肿瘤≥8cm或≥50%肝脏体积)患者经病理学确诊后,给予全肝移动条放射或结合瘤内药物注射的治疗结果。结果提示,放疗结合瘤内药物注射组其治后1年生存率与单纯放疗组近似,而2年生存率则有显著差异(P<0.05)。这说明放疗结合瘤内药物注射有可能提高大肝癌治疗的远期疗效。瘤内药物注射后,患者除有局部轻度胀痛感外,未发现其他副作用。

【Abstract】 This paper reports the response of 62 cases with large primary liver cancer(tumor≥8cm and/or≥50% liver volume) verified by pathology after the treatmentof whole liver irradiation (WLI) by movingstrip technique (MST) or WLI by MSTcombined with intrahepatic injection of drugs. The results suggested that 1-yearsurvival in WLI by MST combined with intrahepatic injection of drugs group wassimilar to that in irradlation group, but 2-year survival was significantly differentbetween two groups (P<0.05), which indicated that the survival of patients withlarge primary liver cancer may be prolonged after treatment of WLI by MST combi-ned with intrahepatic injection of drugs. There were no obvious side-effects duringor after intrahepatic injection of drugs and irradiation.

  • 【被引频次】3
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