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超声对提高胆管疾病诊断率的研究——注射Ceosunin及纵、横旋转扫查法的意义

Ultrasound Study of Common Bile Duct in the Diagnosis of Periampullary Carcinoma Using an Injection of Ceosunin and a Rotational Scanning Technique

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【作者】 陈敏华王彬朱强李建国王旻孟昭敏严昆董宝玮黄信孚丁子清佐藤幸彦岸本理和藤田信行

【Author】 Chen Minhua, Wang Bin, Zhu Qiang, Li Jianguo, Wang Min, Meng Zhaomin, Yan Kun, Dong Baowei, Huang Xinfu (Department of Ultrasonography, Beijing Medical University College of Oncology and Beijing Institute for Cancer Research, Beijing, 100034)

【机构】 北京医科大学临床肿瘤学院日本北海道大学医学部放射线科日本北海道大学医学部放射线科 100034100034100034

【摘要】 对肝外胆管扩张(7—15mm)42例施行了Ceosunin注射后(利胆法)超声观察。被证实胆管有梗阻性病变18例中,72%(13例)胆管增宽,16%(3例)无明显变化,12%(2例)缩小;胆管径均值从9.8mm增宽达11.7mm。非梗阻组24例中92%(22例)胆管径缩小,8%(2例)无明显变化,无1例增宽;胆管径均值从9.6mm缩小至6.3mm。梗阻组中9例壶腹周围癌(其中6例肿瘤径≤2cm)经利胆法后胆管径均增宽,采用胆管纵旋转扫查法及横旋转扫查法,使8例肿瘤得以显示。利胆法及旋转扫查法的应用使胆管下段病变显示率从41%提高到88%。对胆管扩张病例施行利胆法,以管径没有缩小为疑诊胆管梗阻的标准,其Sensitivity为89%,Specificity为92%;Accuracy为90%。本方法对判断胆管轻度扩张的病理意义有较高临床价值。为壶腹周围肿瘤的早期诊断提供了无创伤的手段。

【Abstract】 A total of 42 patients with mild dilatation (7-15mm in diameter) of common bile duct (CBD) were studied by B-mode real-time ultrasound in pre-and post-injection of ceosunin. Of 18 patients who had obstructing lesions of CBD, 13 (72%) cases showed an increase in diameter of CBD after an injection of the cholagogue, 3 (16%) no change and 2 (12%) a decrease. In 24 patients with no obstruction of CBD, 22 (92%) cases presented a contraction of the lumen and 2 (8%) had no reaction following the administration. When CBD had no alteration or a luminal dilatation after the injection, an obstructive disease distally located was strongly suspected, with a sensitivity of 89%, a specificity of 92% and an accuracy of 90%. Furthermore, this ultrasonic method plus employing a rotational scanning technique on the surface of abdomen enabled the clear visualization of 8 periampullary carcinoma foci, of which 6 ones were less than or equal to 20mm in diameter. The paper, therefore, demonstrates that this ultrasonography could differentiate an obstructive from a non-obstructive moderate dilatation of CBD, so that it makes possible the early diagnosis of distal CBD’s or periampullary carcinoma.

  • 【文献出处】 中国医学影像学杂志 ,Chinese Journal of Medical Imaging , 编辑部邮箱 ,1993年00期
  • 【被引频次】5
  • 【下载频次】24
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