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新菌灵治疗呼吸道感染的随机对照试验
A RANDOMIZED CONTROLLED STUDY ON CEFUROXIME AXETIL IN THE TREATMENT OF RESPIRATORY INFECTIONS
【摘要】 用随机对照方法评价了新菌灵250mg 2次/d疗程7~10d治疗上呼吸道感染20例;250~500mg 2次/d 疗程10~14d 治疗下呼吸道感染15例的安全有效性,获得了满意的临床疗效和细菌学结果。上、下呼吸道感染的痊愈率分别为95%与80%;细菌清除率分别为100%与93.33%;不良反应发生率仅为2.85%。新菌灵分别与头孢拉定和头孢克罗随机对照治疗上、下呼吸道感染,试验药与对照药的痊愈率、细菌清除率及不良反应发生率均无显著性差异。
【Abstract】 20 patients with upper respiratory infections were treated with oralcefuroxime axetil 250mg twice daily for 7~10 days and another 15 patients with lowerrespiratory infections were given orally the same drug 250~500mg twice daily for 10~14 days.The cure rate were 95% and 80% respectively.The bacterial clearance rate forthe two group were 100% and 93.33% respectively.There were no statistical differ-ence between treatment and control groups.
【关键词】 新菌灵;
头孢克罗;
头孢拉定;
随机对照;
临床试验;
【Key words】 Cefuroxime axetil; Cephradine; Cefaclor; randomized; Clinical study;
【Key words】 Cefuroxime axetil; Cephradine; Cefaclor; randomized; Clinical study;
- 【文献出处】 中国新药杂志 ,Chinese Journal of New Drugs , 编辑部邮箱 ,1993年05期
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