【摘要】 经胃镜活检组织病理检查,明确诊断胃窦部慢性浅表性胃炎与慢性浅表萎缩性胃炎的肠化生患者72例,分为脾胃虚寒型、肝胃不和型和脾胃阴虚型。治疗组37例,按型分别用脾胃平胶囊Ⅰ、Ⅱ、Ⅲ号治疗;对照组35例,三型均用三九胃泰治疗。经3～6个月治疗,肠化生治愈率和总有效率,治疗组为43.2％、59.5％;对照组为20.0％、34.3％,差异非常显著,P<0.01。胃粘膜DNA和cAMP含量的改善,细胞免疫功能的提高;治疗组优于对照组,P<0.01～0.001。说明肠化生是可逆的,中成药辨证论治其可逆性疗效更佳。更多还原

【Abstract】 After gastroscope and pathological examination of biopsy 72 patients with antral chronic superficial or atrophic gastritis concomitant intestinal metaplasia were divided into two groups and given 3 - 6 months treatment. 37patients of treatment group were respectiverly treated by Piweiping Capsule Ⅰ(insufficiency of the spleen-yang),Piweiping Capsule Ⅱ (deficiency of the spleen-ying)and Piweiping Capsule Ⅲ(inco ordination between the liver and stomach)。 35 patients of control group were treated by Sanjiuweitai。The results showed the cure rate of intestinal metaplasia was 43. 2% ,but 20. 0% in control group(p<0. 001 -0. 01). Total effective rate was 59. 5%,but 34. 3%in control group(P<0. 01-0. 001). The treatment group in improving the content of gastric mucosal DNAand CAMP and cellular immune function were supe rior to the those control group(P<0. 01 - 0. 001).The results suggested that the intestinal metaplasia was reversible and can get still better effect treated by syndrome differentiation of TCM.更多还原