【摘要】 自芸香科花椒属植物竹叶椒（Zanthoxglum planispinum Sieb.et Zucc）根和茎的石油醚及二氯甲烷提取物中分离得到5个化合物（I～V）,经物理常数测定,光谱（UV,IR,HNMR,MS）分析分别鉴定,Ⅰ为β-香木脂醇,Ⅱ为β-谷甾醇,Ⅲ为L-细辛脂素,Ⅳ为L-竹叶椒脂素,V为花椒明碱。其中Ⅲ,IV,V具有抑制PAF聚集的活性,以Ⅳ活性最强,Ⅲ次之,V较弱。花椒明碱首次从该植物中分离得到。更多还原

【Abstract】 Five compounds were isolated from the petroleum ether and methylene chloride extracts of the roots and stems of Zanthoxylum planispinum Sieb. et Zucc. (Rutaceae). The structure of these compounds were determined on the basis of physical constant and UV, IR, ~1HNMR, MS spectral analysis. They are β-amyrin ( I ) , β-sitosterol ( Ⅱ ) , L-asarinin ( I ) , L-planinin ( IV ) and zanthobungeanine ( V ) respectively. Compound I 、 IV 、 V showed obviously inhibitoryactivity to platelet aggregation caused by PAF, among them compound Ⅲ was less active than compound V , compound V was the least. Zanthobungeanine was isolated for the first time from this plant.更多还原